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KMID : 0942820120110020127
Journal of Korean Brain Tumor Society
2012 Volume.11 No. 2 p.127 ~ p.132
Glioblastoma of the Pineal Gland
Kang Moo-Sung

Hong Chang-Ki
Kim Se-Hoon
Lee Kyu-Sung
Abstract
Pineal gland tumors comprise 0.4-1% of adult intracranial tumors. Glioblastoma, which is the most frequent glioma in brain tumors, is extremely rare in the pineal region.
A 74-year-old man complaining of gait disturbance, urinary incontinence, and memory disturbance underwent ventroperitoneal (VP) shunt under the impression of obstrctive hydrocephalus that occurred secondarily to a tumor in the pineal gland. He refused treatment for the tumor. The symptoms were improved after the VP shunt. Six months postoperatively, he experienced a reaggravation of symptoms. An increase in tumor size was disclosed in brain imaging studies. The patient underwent an occipital craniotomy with occipital trans-tentorial approach. Pathological findings were consistent with glioblastoma. This case emphasizes the importance of considering glioblastoma as a differential diagnosis of pineal gland tumors, particularly if peritumoral heterogenous enhancement is observed. The role of surgery, chemotherapy, and radiotherapy on survival duration is not yet well established. Therefore, studies exploring the effect of each modalities on survival duration are needed.
KEYWORD
Pineal gland, Glioblastoma
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